Summary
Overview
Work History
Education
Skills
PUBLICATIONS
PRESENTATIONS
ACQUIRED GRANT PROPOSAL
ACADEMIC PEER REVIEWING ACTIVITY
ORGANISATION OF CONFERENCE
EXTRACURRICULAR ACTIVITIES
ENGLISH LANGUAGE QUALIFICATION
INTERESTS/HOBBIES
REFERENCE
Timeline
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Mohsen Mahdavimehr

Institute Of Biochemistry And Biophysics, University Of Tehran, Tehran 1417614335, Iran

Summary

A biochemistry graduate specializing in amyloidosis, synthesis of neuroprotective nanomaterials, cell culture, and animal models. Recognized for punctuality, strong problem-solving, proactive approach, creativity, and leadership skills. I'm an adaptable team player with a positive attitude, eager to leverage my research background to drive breakthroughs in healthcare, particularly in the realm of neurodegenerative diseases

Overview

5
5
years of professional experience

Work History

Researcher

Institute of Biochemistry and Biophysics, University of Tehran
Tehran
09.2019 - Current
  • Project title: Inhibition of VEGFR1/R2 using peptide conjugated iron oxide nanoparticles for inhibition of growth and imaging of murine breast tumor

Education

Master of Science - Biochemistry

IASBS
Zanjan, Iran
08-2018

Bachelor of Science - Genetics

Islamic Azad University of Varamin
Iran
08-2014

Skills

Analytical chemistry techniques:

UV-Vis

Fluorescence

FTIR

CD

DLS

AFM

Cell culture techniques:

Aseptic technique

Media preparation

Cell seeding and passaging

MTT assay

LDH Assay

Wound healing assay

Fluorescence microscopy:

Fluorophore labeling

Image processing and analysis

Live cell imaging techniques

Ligand binding assay

Protein expression and purification:

Expression induction and optimization

Cell lysis and protein extraction

Chromatography

Gel electrophoresis:

SDS-PAGE

Native PAGE

Imaging techniques:

MRI

PET

SPECT

Animal models and in vivo experiments:

Animal housing and care

Administration of treatments or interventions

Tissue sample collection

Implanting tumors

Design and synthesis of nanoparticles for drug delivery and imaging applications:

Metal nanoparticles

Polyphenols-based nanoparticles

Polymeric nanoparticles

Graphene oxide nanosheets

PUBLICATIONS

· S. Jalili, M. Panji, M. Mahdavimehr, A. Mohseni Ahangar, H. Shirzad, S.A. Mousavi Nezhad, F.L. Palhano, Enhancing anti-amyloidogenic properties and antioxidant effects of Scutellaria baicalensis polyphenols through novel nanoparticle formation, Int. J. Biol. Macromol. 262 (2024). https://doi.org/10.1016/j.ijbiomac.2024.130003.

· E.R. Ghareghozloo, M. Mahdavimehr, A.A. Meratan, N. Nikfarjam, A. Ghasemi, B. Katebi, M. Nemat-Gorgani, Role of surface oxygen-containing functional groups of graphene oxide quantum dots on amyloid fibrillation of two model proteins, PLoS One 15 (2020) 1–19. https://doi.org/10.1371/journal.pone.0244296.

· M. Mahdavimehr, B. Katebi, A.A. Meratan, International Journal of Biological Macromolecules Effect of fi brillation conditions on the anti-amyloidogenic properties of polyphenols and their involved mechanisms, Int. J. Biol. Macromol. 118 (2018) 552–560. https://doi.org/10.1016/j.ijbiomac.2018.06.109.

· B. Katebi, M. Mahdavimehr, A.A. Meratan, A. Ghasemi, M. Nemat-Gorgani, Protective effects of silibinin on insulin amyloid fibrillation, cytotoxicity and mitochondrial membrane damage, Arch. Biochem. Biophys. 659 (2018) 22–32. https://doi.org/10.1016/j.abb.2018.09.024.

· M. Mahdavimehr, A.A. Meratan, M. Ghobeh, A. Ghasemi, A.A. Saboury, M. Nemat-Gorgani, Inhibition of HEWL fibril formation by taxifolin: Mechanism of action, PLoS One 12 (2017) 9–11. https://doi.org/10.1371/journal.pone.0187841.

PRESENTATIONS

Poster

· Amyloidogenic conditions may dramatically bias antiamyloidogenic properties of polyphenols, 3rd National Conference on Protein and Peptide Sciences, April 25 & 26, 2018, Shiraz.

· Investigating the anti-Amyloidogenic and antioxidant properties of novel natural polyphenol-based nanoparticles. 1th conference on modern biotechnology. August 29 & 30, 2023, Tehran.

Oral talk

· Improvement of Breast tumor Imaging by Multifunctional SPION Nanoparticles Conjugated with a Novel Engineered Endostatin Peptide, 6th Annual International TPCF Preclinical Imaging Symposium, November 8 & 9, 2023, Tehran

ACQUIRED GRANT PROPOSAL

  • · Iran National Science Foundation (INSF) grant (200,000,000 Rials), February 2023 (Project: Inhibition of VEGFR1/R2 using peptide conjugated iron oxide nanoparticles for inhibition of growth and imaging of murine breast tumor).

ACADEMIC PEER REVIEWING ACTIVITY

  • · Reviewing manuscripts for International Journal of Biological Macromolecules

ORGANISATION OF CONFERENCE

  • Public relations director of 3rd IASBS Symposium in Biological Sciences Protein Folding and Stability. November 2-4, 2017, Zanjan

EXTRACURRICULAR ACTIVITIES

  • 2016 – 2018, Secretary of the students' scientific association of biology in IASBS, Zanjan, Iran

ENGLISH LANGUAGE QUALIFICATION

  • Proficient in English with a Duolingo score of 110.

INTERESTS/HOBBIES

· Accomplished climber

· Adventurous tracker

· Leisure swimmer

· Passionate weekend chef

REFERENCE

Dr. Ali Akbar Meratan: Associate Professor of Biochemistry; PhD.

Tel: (+98) 24 3315 3309,

Email: a.meratan@iasbs.ac.ir

Timeline

Researcher

Institute of Biochemistry and Biophysics, University of Tehran
09.2019 - Current

Master of Science - Biochemistry

IASBS

Bachelor of Science - Genetics

Islamic Azad University of Varamin
Mohsen Mahdavimehr