Summary
Overview
Work History
Education
Skills
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RESEARCH EXPERIENCE
Certification
Languages
Timeline
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GAYATHRI SIVASAILAM

Dublin,Ireland

Summary

Dynamic and goal-oriented Computational Research Intern, eager to channel a robust academic background, strong laboratory skills, and unwavering enthusiasm for immunology toward crafting innovative solutions within the pharmaceutical sector. Currently immersed in a transformative project on the Computational Prediction of Improved antimicrobial peptide (AMP) Availability and Function, collaborating with esteemed immunologists and industry professionals. Proficient in utilizing Bioinformatics tools like 'Alpha Fold' to contribute meaningfully to the commercial potential and applications of novel AMPs.

Overview

2
2
years of professional experience
4
4
years of post-secondary education
1
1
Certification

Work History

Research intern

Trinity College Dublin
Dublin, Ireland
01.2024 - 07.2024

As an intern in MSc Immunotherapeutics Placement 2024 program, I actively contribute to ongoing project focused on Computational Prediction of Improved Anti-Microbial Peptide (AMP) Availability and Function. In collaboration with Trinity Research & Innovation and under guidance of academic leads Cliona O’Farrelly and Kieran Meade, my responsibilities include:

  • Exploring commercial potential and applications of project in collaboration with Trinity Technical Transfer Team.
  • Utilizing Bioinformatics tools such as Alphafold and other computational biology tools for predicting AMP function.
  • Leading preparation and submission of proposals for EI Commercial Feasibility Scheme.

This role allows me to apply my skills in computational biology, data analysis, and project management within dynamic field of immunology research, contributing to development of potential therapeutic solutions in context of antibiotic-resistant bacteria.

Laboratory intern

Bionyme Laboratories
Chennai
04.2022 - 04.2022
  • Carried out routine housekeeping tasks to maintain safe, clean, uncluttered work environment.
  • Adopted aseptic techniques to maintain sample integrity.
  • Followed instructions to prepare precise chemical solutions for laboratory use.
  • Prepared samples through homogenizing, freeze-drying, and weighing.
  • Operated complex scientific equipment with care and precision.
  • Handled samples in line with strict laboratory procedures using appropriate PPE.

Education

Master of Science - Immunotherapeutics

Trinity College Dublin
Dublin
09.2023 -

Bachelor of Technology - Biotechnology

St. Joseph’s College of Engineering
Chennai
07.2019 - 04.2023

Skills

  • Problem-solving
  • Marketing
  • Communication skills
  • Time management
  • Knowledge of Computational Biology tools

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RESEARCH EXPERIENCE

  • TNSCST GOVT FUNDED PROJECT Jan 2023- May 2023

“Synthesis of reduced graphene oxide using modified Hummer’s method for cancer treatment.”

This project aims to create a cancer treatment drug candidate through an environmentally friendly process. The process involved using natural sources, including Valonia utricularis and leaf extract of Coriandrum sativum to synthesise a biocompatible magnetic reduced graphene oxide (rGO/Fe2O3). The results obtained indicated that the nanocomposite possesses magnetic properties, making it suitable for targeted anti-cancer treatments. Furthermore, its remarkable biocompatibility suggests its potential as a drug delivery system.

· “Synthesis of rGO/IONP using bio-synthesis method and studying its anti-oxidant, anti-inflammatory, haemolysis and anti-diabetic property.” Nov 2022- April 2023

The project involves production of rGO nanoparticles from Valonia utricularisthrough thermal degradation and combines them with iron nanoparticles from coriander leaf extract to create a nanocomposite with impressive anti-oxidant, anti-inflammatory, haemolysis, and anti-diabetic properties.

Certification

  • Advancements in Drug Designing by E-Cell in IIT Kharagpur. (Jan 2023)
  • A Practical Guide for SARS-CoV-2 Whole Genome Sequencing offered by COG-UK. (Jan/2023)
  • Clinical Trial Analysis and Reporting by Internshala Trainings. (March 2022)
  • The Power of Genomics to Understand the Covid-19 Pandemic offered by Wellcome Connecting Science and COG-UK. (Feb 2022)
  • Bacterial Genomes III: Comparative Genomics using Artemis Comparison tool offered Wellcome Connecting Science. (Sept 2021)
  • Bacterial Genomes II: Accessing and Analysing Microbial Genome Data using Artemis offered Wellcome Connecting Science. (July 2021)
  • Bacterial Genomes I: From DNA to Protein function using Bioinformatics offered by Wellcome Connecting Science. (May 2021)
  • Bacterial Genomes-AMR in Bacterial Pathogens offered by Wellcome Connecting Science. (May 2021)
  • Bacterial Genome-Disease Outbreaks and Antimicrobial Resistance offered by Wellcome Connecting Science. (April 2021)
  • The Science of Stem cells authorised by American Museum of Natural History and offered through Coursera. (April 2021)
  • Drug discovery authorised by University of California San Diego and offered through Coursera. (Aug 2020)

Languages

English
Advanced (C1)

Timeline

Research intern

Trinity College Dublin
01.2024 - 07.2024

Master of Science - Immunotherapeutics

Trinity College Dublin
09.2023 -

Laboratory intern

Bionyme Laboratories
04.2022 - 04.2022

Bachelor of Technology - Biotechnology

St. Joseph’s College of Engineering
07.2019 - 04.2023
  • Advancements in Drug Designing by E-Cell in IIT Kharagpur., 01/2023
  • A Practical Guide for SARS-CoV-2 Whole Genome Sequencing offered by COG-UK., 01/2023
  • Clinical Trial Analysis and Reporting by Internshala Trainings., 03/2022
  • The Power of Genomics to Understand the Covid-19 Pandemic offered by Wellcome Connecting Science and COG-UK., 02/2022
  • Bacterial Genomes III: Comparative Genomics using Artemis Comparison tool offered Wellcome Connecting Science., 09/2021
  • Bacterial Genomes II: Accessing and Analysing Microbial Genome Data using Artemis offered Wellcome Connecting Science., 07/2021
  • Bacterial Genomes I: From DNA to Protein function using Bioinformatics offered by Wellcome Connecting Science., 05/2021
  • Bacterial Genomes-AMR in Bacterial Pathogens offered by Wellcome Connecting Science., 05/2021
  • Bacterial Genome-Disease Outbreaks and Antimicrobial Resistance offered by Wellcome Connecting Science., 04/2021
  • The Science of Stem cells authorised by American Museum of Natural History and offered through Coursera., 04/2021
  • Drug discovery authorised by University of California San Diego and offered through Coursera., 08/2020
GAYATHRI SIVASAILAM